Cephalexin

C. diff Risk

Medium

Oral Bioavailability

Good (70 to 90%)

Approximate Cost

$0.44/day

Dosing

500-1000mg PO QID

General Information

Common Usage

  •  Uncomplicated skin and soft tissue infection

  •  MSSA infections

Adverse Effects

  •  Allergy/rash (immediate or delayed)

  •  Positive Coombs

  •  Cytopenias

  •  Eosinophilia

  •  Hepatic & renal laboratory abnormalities

Tablet/Capsule Strengths

OPEN BENEFIT
No prescribing restrictions

Additional Information

EH Prescribing Restrictions
None

Tablets can be crushed and given via NG route; Liquid formulation also available

Pharmacology

Antimicrobial class: First Generation Cephalosporin.

Pregnancy category: B

Urine penetration: Therapeutic

Lung penetration: Moderate

CSF penetration: Poor

Biliary penetration: Moderate