1-2g IV q4-6h
2g IV q4h for meningitis or endocarditis
Pathogen directed therapy for CNS, intravascular, intraabdominal, urinary and other infections especially Enterococcus and Listeria
Allergy and rash as for all beta-lactams.
EBV related rash (not allergy).
Rare: cytopenias, +ve Coombs.
Increased risk of rash with allopurinol.
OPEN BENEFIT (PO)
No prescribing restrictions
- Dilute in 50-100 mL NS and administer over 30 min.
- Max concentration 30 mg/mL.
Prescribing Restrictions (IV)
- Ampicillin PO orders are automatically substituted with Amoxicillin PO at Eastern Health
Community IV Formulary (St. John’s Metro)
- Limited Stability of IV ampicillin precludes use in Community IV program.
Antimicrobial class: Aminopenicillin
Pregnancy category: B
Average serum half life: 1 hour
Biliary penetration: Therapeutic
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic