1-2g IV q4-6h
2g IV q4h for meningitis or endocarditis
Pathogen directed therapy for CNS, intravascular, intraabdominal, urinary and other infections especially Enterococcus and Listeria
Allergy and rash as for all beta-lactams.
EBV related rash (not allergy).
Rare: cytopenias, +ve Coombs.
Increased risk of rash with allopurinol.
OPEN BENEFIT (PO)
No prescribing restrictions
Dilute in 50-100 mL NS and administer over 30 min.
Max concentration 30 mg/mL.
Prescribing Restrictions (IV)
Ampicillin PO orders are automatically substituted with Amoxicillin PO at Eastern Health
Community IV Formulary (St. John’s Metro)
Limited Stability of IV ampicillin precludes use in Community IV program.
Antimicrobial class: Aminopenicillin
Pregnancy category: B
Average serum half life: 1 hour
Biliary penetration: Therapeutic
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic