The manufacturer provides no dosing guideline. Not studied.
Severe Impairment (Child-Pugh Class C)
70 mg IV once then 35 mg IV daily
Moderate Impairment (Child-Pugh Class B)
No adjustment required
Mild Impairment (Child-Pugh Class A)
No dose adjustment required.
Poorly dialyzed, no supplemental doses required in hemodialysis.
Therapy of suspected and confirmed invasive fungal infections
- Increased liver enzymes
- GI upset
- NS only (incompatible with D5W).
- Dilute in 250 mL NS, infuse over 60 min.
EH Prescribing Restrictions
Community IV Formulary (Metro Area)
Antimicrobial class: Echinocandin
Pregnancy category: C
Average serum half life: 10 hours
Urine penetration: Poor
Biliary penetration: Therapeutic
Lung penetration: Therapeutic
CSF penetration: Poor