5 mg/kg IV q24h
5 mg/kg IV q12h
CBC with differential twice weekly.
Serum creatinine once weekly.
May cause blood dyscrasias:
Usually within first 1-2 weeks of treatment. Generally resolves within 3-7 days of discontinuation.
Hazardous drug must be prepared by Pharmacy
Prepared in 100 mL NS. Infuse over 60 min
EH Prescribing Restrictions
Community IV Formulary (Metro Area)
Antimicrobial class: Antiviral, binds DNA polymerase to inhibit viral DNA synthesis.
Pregnancy category: C - animal studies have demonstrated carcinogenic and teratogenic effects.