Extended Spectrum Beta-Lactamase (ESBL) Producing Organisms

Precautions

Routine Practices
Routine Practices

General Information

Pathogen information

Gram negative organisms with enzymes that confer resistance to all cephalosporins.

Epidemiology

Generally, normal GI flora that have a plasmid encoding ESBL.

Community-acquired and nosocomial infections occur, especially if patient has received antimicrobials or has travelled to areas of high prevalence (i.e. Asia/India).

Human-to-human transmission occurs and outbreaks have beed described.

Can also pick up from environment/water, surfaces, animals, and meat.

Associated syndromes

  • Asymptomatic colonization

  • Any syndrome caused by the organism carrying it (see specific organism for more information)

Additional Information

ESBLs vs. AmpC: Most ESBLs are plasmid-encoded, whereas AmpCs are usually inducible and chromosomal.