Tendinopathy and rupture
Weakness exacerbation in myasthenia gravis
CNS toxicity including confusion, psychosis.
Pseudomonal and other gram negative infections of urinary tract, bone/joint, abdomen and other sites.
Monitor QTc in patients with increased risk.
Other QTc prolonging agents
Divalent cations - Decreased absorption
NSAIDs - Increase seizure risk
Warfarin - Increased INR
Antimicrobial class: Fluoroquinolone
Pregnancy category: C
Average serum half life: 4 hours
Biliary penetration: Therapeutic
CSF penetration: Moderate
Lung penetration: Therapeutic
Urine penetration: Therapeutic