Antimicrobials
Clindamycin

Clindamycin

High
Excellent
See below

Spectrum of Activity

Dosing

General Information

  • N35-60/150mg tab
  • N150/300mg tab
  • N1800/vial
  • Anaerobic infections above the diaphragm, especially dental infection.
  • Gram positive skin and soft tissue infections including necrotizing fasciitis as an adjunctive agent to a beta lactam for reducing toxin production.
  • Skin & soft tissue infections involving susceptible MRSA.
  • Susceptible infections and surgical prophylaxis in setting of IgE mediated beta-lactam allergy.
  • For decreasing toxin production in toxic shock syndrome.

None specific.

Monitor for diarrhea.

  • Diarrhoea
  • Nausea
  • Pseudomembranous colitis
  • Skin rash
  • Erythema multiforme
  • ALT elevation
  • AST elevation
  • Thrombocytopenia
  • Leucopenia

Muscle relaxants, e.g., atracurium, baclofen, diazepam.

St. Johns Wort.

Antimicrobial class: Lincosamide

Pregnancy category: B

Average serum half life: 2.4 hours

Urine penetration: Poor

Lung penetration: Therapeutic

CSF penetration: Poor

Biliary penetration: Therapeutic