40 kg and less:
IV/IM 100mg/kg/DAY divided q12h. Max: 2g/dose.40 kg and greater:
IV/IM 1-2g q12h Febrile Neutropenia:
IV/IM 150mg/kg/DAY divided q8h. Max: 2g/dose
PNA <14 days:
IV: 60-100mg/kg/DAY divided q12hPNA 14 days or older:
IV 100mg/kg/DAY divided q12h
Renally cleared, requires dosage adjustment with changes in renal function. Consult a pharmacist for renal dosing.
Broad spectrum antimicrobial with gram positive and gram negative coverage including Pseudomonas.
Used especially nosocomial infections involving resistant organisms
Allergy (immediate or delayed).
Can cause positive Coombs, cytopenias.
Antimicrobial class: 4th generation Cephalosporin
Average serum half life:
Children 2 months to 6 years: 1.77-1.96 hours.
Adult: 2 hours
Route of Elimination: At least 85% eliminated as unchanged drug in urine