Antimicrobials
CefTAZidime

CefTAZidime

High
N/A

General Information

Broad gram negative coverage including Pseudomonas, generally used for nosocomial infections including post-neurosurgical meningitis, or other infections based on susceptibilities.

Notable lack of gram positive activity versus other cephalosporins

Allergy (immediate and delayed)- note potential cross-reactivity with aztreonam based on side chain

Antimicrobial class: 3rd generation Cephalosporin

Average serum half life:

  • neonates <23 days: 2.2-4.7 hours
  • adults: 1-2 hours

Route of Elimination: by glomerular filtration with 80-90% of dose excreted as unchanged drug in urine within 24 hours.