3 mg/kg/DOSE PO BID x 5 days
0 - 15 kg15 - 23 23 - 40 kg40+ kg30 mg/DOSE PO BID x 5 days45 mg/DOSE PO BID x 5 days60 mg/DOSE PO BID x 5 days75 mg/DOSE PO BID x 5 days
75 mg/DOSE PO BID x 5 days
Limited data available on dosing in neonates.
Oral: 1 mg/kg/DOSE twice daily; duration not determined.
PNA-days 0 - 13PNA-days 14 - 28 Oral: 3 mg/kg/DOSE once daily for 5 daysOral: 3 mg/kg/DOSE twice daily for 5 days
Renally cleared, requires dosage adjustment with changes in renal function. Consult a pharmacist for renal dosing.
GI upset common
Rare - Stevens Johnson Syndrome
Neuropsychiatric side effects reported
Antimicrobial class: Antiviral - neuraminidase inhibitor
Average serum half life:
No pediatric data available.
Adult: Oseltamivir phosphate: 1-3 hours, oseltamivir carboxylate: 6-10 hours
Route of Elimination: Hepatically metabolixed to >99% of oseltamivir carboxylate (active metabolite) is eliminated by renal excretion via glomerular filtration and tubular secretion
