C difficile risk
Oral Bioavailability


Urinary tract infection, uncomplicated

NOTE: Limited data available

  • Children <12 years: 2 grams PO as a single dose

  • Children ≥12 years and Adolescents: 3 grams PO as a single dose

NOTE: Oral formulation should NOT be used for pyelonephritis or perinephric abscess etc.

General Information

Urinary Tract Infection, especially involving ESBL producing organisms

NOT recommended in pyelonephritis

  •  GI upset, especially diarrhea

  •  Headache

  •  Eosinophilia, neutropenia

  •  Hypokalemia

Antimicrobial class: Phosphonic acid derivative

Pregnancy category: B

Average serum half life: 6 hours

Urine penetration: Therapeutic