Fever in Asplenic/Sickle Cell Patients

Note

This guideline is intended for Empiric Hospital Therapy

Modify therapy when possible according to identified pathogens, antimicrobial susceptibility and clinical status

Patient showing signs of shock

  • Give q12 for meningitis/CNS infections

  • Max 4g/day

AND

  • Usual maximum starting dose 4g/day

  • Dose should be adjusted based on serum drug level monitoring