This guideline is intended for Empiric Hospital Therapy
Modify therapy when possible according to identified pathogens, antimicrobial susceptibility and clinical status
Ceftriaxone IV/IM 100 mg/kg/day divided q12-24 hrs
Give q12 for meningitis/CNS infections
Vancomycin IV 60 mg/kg/day divided q6-8 hrs.
Usual maximum starting dose 4g/day
Dose should be adjusted based on serum drug level monitoring
Ceftriaxone IV/IM 50-75 mg/kg/day given as a single daily dose