Antimicrobials
Primaquine Phosphate

Primaquine Phosphate

N/A
N/A
PO: $

General Information

Used after chloroquine treatment of P. vivax and P. ovale malaria for "radical cure" as it has activity against liver stage; not used as a single agent

May cause massive hemolysis in patients with G6PD deficiency; consider G6PD testing prior to use

Tablet: 26.3mg (= 15mg primaquine base)

  • Give with food to mask bitter taste
  • Primaquine should be considered an "alternate" prophylactic medication if the patient is unable to tolerate first line prophylaxis medications (such as atovaquone/proguanil [Malarone], mefloquine or doxycycline)