1g IV q24h
CrCl Greater Than 30 mL/minCrCl Less Than 30 mL/min1 g q24h500 mg q24h
Immediate and delayed-type allergy
Cytopenias, eosinophilia, positive Coombs
Liver enzyme abnormalities
Seizure risk lower than other carbapenems
Antimicrobial class: Carbapenem
Pregnancy category: B
Average serum half life: 4 hours
Biliary penetration: Moderate
Lung penetration: Therapeutic
Urine penetration: Therapeutic
Targeted therapy of ESBL infections and other resistant gram negative infections.
Empiric therapy when broad spectrum of carbapenems is desired without the need for anti-pseudomonal activity.