Cefepime
Renal

Renal

In the setting of rapidly improving or worsening renal function, calculations of CrCl are inaccurate. Dosing should be based on estimated renal function instead.

If improving renal function, actual CrCl is likely higher than calculated CrCl.

If worsening renal function, actual CrCl is likely lower than calculated CrCl.

Not On Dialysis

CrCl Greater Than 60 mL/min

2 g IV q8-12h

CrCl 30-50 mL/min

2g IV q12-24h

CrCl 11-29 mL/min

1-2g IV q24h

CrCl Less Than 11 mL/min

500mg-1g IV q24h