Nitrofurantoin
Renal

Renal

In the setting of rapidly improving or worsening renal function, calculations of CrCl are inaccurate. Dosing should be based on estimated renal function instead.

If improving renal function, actual CrCl is likely higher than calculated CrCl.

If worsening renal function, actual CrCl is likely lower than calculated CrCl.

Renal Dosing

CrCl Greater Than 30 mL/min

100 mg PO BID

CrCl Less Than 30 mL/min

Nitrofurantoin should be avoided