Penicillin VK

C. diff Risk


Oral Bioavailability



125-500mg PO q6-8h

Discuss indication specific dose recommendations with ID or ASPAdminister around-the-clock to promote less variation in peak and trough serum levels.

General Information

  • ┬áMonitor for allergy.

  • ┬áPeriodic CBC, SCr

  • Allergy (anaphylaxis) and other rash

  • Cytopenias, Positive Coombs, Eosinophilia

  • Serum sickness

  • AIN

No significant interactions

Antimicrobial class: Penicillin

Pregnancy category: B

Average serum half life: 1 hour

Lung penetration: Therapeutic

Urine penetration: Therapeutic

Streptococcal infections and therapy of documented susceptible infection not requiring parenteral therapy (i.e. upper respiratory tract).

Prophylaxis after rheumatic fever.