ID consultation is recommended
Surgical consultation as applicable for debridement
PLUS*
*If signs of hemodynamic instability
Minimum 14 days from negative blood culture.
Tailor duration based on source of bacteremia.
Most common source is SSTI. Others include:
When the suspected source of infection may be polymicrobial then broader spectrum coverage is recommended.
May narrow to monotherapy (penicillin preferred) once there are no further signs of systemic infection and no further surgical intervention (e.g. if requires debridement or fasciotomy).