Antimicrobials
Colistin

Colistin

Medium
N/A
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Spectrum of Activity

General Information

  • Management of infections due to multi-drug resistant Enterobactericiae, Acinetobacter, and Pseudomonas on a case-by-case basis
  • Infections due to non-MDR pathogens for which alternate therapy, particularly beta-lactam antibiotics, are available
  • Prophylaxis

Severe infectious caused by multidrug-resistant Gram-negative organisms when other antimicrobial options are limited

Laboratory

  • CBC, BMP 2x/ weekly

Clinical

  • Monitor for nephrotoxicity and neuromuscular blockade.
  • Nephrotoxicity in up to 20% of patients
  • Phlebitis at infusion sites
  • Neurotoxicity
  • Inhaled form: Possible bronchospasm, ARDS

Pregnancy category: C