125 mg PO/NG/OG q6h for 10-14 days
Intra-colonic dose 500 mg in 100mL of NS by rectal enema q6h
Life-threatening infection or ileus: 500 mg PO/NG/OG q6h
Possibility of accumulation in severe renal dysfunction.
Consider checking a vancomycin level in dialysis patients
No oral absorption.
May increase vancomycin resistant enterococci colonization in the gut.
Antimicrobial class: Glycopeptide
Pregnancy category: B
Average serum half life: 0 hours
Biliary penetration: None
CSF penetration: None
Lung penetration: None
Urine penetration: None
Only indication is in the therapy of C. difficile infection, particularly recurrent disease