Guidelines
Neonatal HSV

Neonatal HSV

Neonatal Symptoms

  • Check skin, eye including conjunctivitis and mucous membranes for lesions
  • CNS involvement or encephalitis and may have vesicular skin lesions
  • May involve multiple organ systems such as lungs, liver, adrenal glands, CNS and can have vesicular skin lesions
  • Consider HSV in neonates with sepsis syndrome or disproportionate liver dysfunction
  • Consider if no improvement on antibiotics for >24 hrs
  • Consider HSV in neonates with fever, irritability, abnormal CDF findings, thrombocytopenia and seizures
  • Normal CSF cell count and biochemical parameters do not exclude neonatal HSC CNS infection