C. diff Risk


Oral Bioavailability


Approximate Cost


Spectrum Of Activity


500 mg PO q12h

Renally cleared, requires dosage adjustment with changes in renal function. Consult a pharmacist for renal dosing

General Information

Common Usage

Community-acquired pneumonia, otitis media, uncomplicated skin and skin structure infections

Adverse Effects

  • Allergy (cefprozil and amoxicillin have the same side chain, hence cross -allergenicity may occur)

  • Positive Coombs

  • Cytopenias

  • GI upset, diarrhea

  • Abnormal liver enzymes

Oral Liquids

Concentration: 50 mg/mL
Taste: palatable
Not all strengths of oral liquids are listed nor are available on IWK formulary

Tablet/Capsule Strengths

250 mg tablet
Tablets and capsules are preferred especially over an unpleasant tasting liquid.
Not all strengths of oral tablets/capsules are listed and they are not all available on the IWK formulary.


Antimicrobial class: 2nd Generation Cephalosporin