Targeted or empiric therapy for gram positive infections including skin and soft tissue, and pneumonia.
Covers MRSA and Vancomycin resistant Enterococcus.
Has toxin mediating effects with Strep (similar to clindamycin).
CBC at least once/week
Visual testing for therapy >3 months or if symptoms develop on therapy
SSRI and other serotonergics/MAOIs - Increased risk of serotonin syndrome.
Rifampin decreases linezolid levels.
Restricted to Infectious Diseases
Antimicrobial class: Oxazolidinone
Pregnancy category: C
Average serum half life: 5 hours
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic