2 g IV q4h OR 12 grams continuous infusion over 24 hours
Serious MSSA infections (CNS, Endocarditis)
CBC weekly - Monitor for neutropenia
Generally reserved for the more serious MSSA infections.
More side effects and more costly than cefazolin.
Antimicrobial class: antistaphylococcal penicillin
Pregnancy category: B
Average serum half life: 0.5 to 1 hour
CSF penetration: Drug of choice for MSSA brain abscess
Route of Elimination: hepatic
No renal adjustment required