Order upon presentation. PCT testing is reasonable to reduce unnecessary antibiotic exposure.
Antibiotic initiation strongly discouraged
Alternative diagnosis of viral infection or pulmonary embolism may be considered
Consider antibiotic initiation if patient becomes clinically unstable or has strong evidence of bacterial pathogen
Antibiotic initiation discouraged
Alternative diagnosis of viral infection or pulmonary embolism may be considered
Consider antibiotic initiation if patient becomes clinically unstable or has strong evidence of bacterial pathogen
Repeat PCT monitoring at 48-72 hours
PCT can be effective every 48-72 hours to reduce duration of antimicrobial therapy in stable patients with concern for respiratory tract infections
See "Thresholds for Antibiotic De-Escalation" below
PCT should not be used in place of standard diagnostic tests.
It is a biomarker to aid a clinician in decision making. Algorithm should not circumvent clinical judgement and patient assessment.