400 mg IV/PO daily
No dose adjustment
Low urinary drug levels - do not use to treat UTI.
May exacerbate muscle weakness in persons with myasthenia gravis. Avoid Use.
CNS toxicity including confusion, psychosis
Tendinopathy and rupture
Weakness exacerbation in myasthenia gravis
Monitor QTc in patients with increased risk
QTc prolongation - Increased risk with other agents that prolong QTc
Divalent cations including Ca, Mg - decreased absorption
Warfarin - increased INR
Rifampin - decrease moxifloxacin levels
Antimicrobial class: Fluoroquinolone
Pregnancy category: C