Cephalexin

C. diff Risk

Medium

Oral Bioavailability

Moderate

Spectrum Of Activity

Dosing

500 mg PO QID

30+ mL/min10 - 30 mL/min0 - 10 mL/min500 mg PO QID500 mg PO TID500 mg PO BID

Give dose after dialysis on dialysis days500 mg PO BID

500 mg PO BID

General Information

Adverse Effects

Allergy/rash (immediate or delayed).

Can cause positive Coombs, cytopenias, eosinophilia, and hepatic and renal laboratory abnormalities.

Major Interactions

May increase metformin levels.

Pharmacology

Antimicrobial class: First generation cephalosporin - oral.

Pregnancy category: B