Amoxicillin

C. diff Risk

Low

Oral Bioavailability

Excellent

Dosing

500-1000 mg PO TID

30+ mL/min10 - 30 mL/min<10 mL/min500-1000 mg PO TID500 mg PO BID500 mg PO BID

Take after dialysis on HD days 500 mg PO BID

500 mg PO BID

General Information

Adverse Effects

Allergy/rash (immediate or delayed), cytopenias. Note EBV related rash.

Major Interactions

Allopurinol - increased rash

Pharmacology

Antimicrobial class: Aminopenicillin

Pregnancy category: B