Clostridium tetani


Standard Precautions
Standard Precautions

General Information

Pathogen information

Anaerobic gram positive spore-forming bacilli

Clinical disease results from toxin (tetanospasmin)


Unvaccinated (incompletely vaccinated) individuals with wound (portal of entry).

Associated syndromes

Forms of Tetanus:
1. Generalized
2. Localized
3. Cephalic
4. Neonatal

Additional Information

Wound prophylaxis:
Tetanus immunoglobulin/Td vaccination may be necessary. Refer to Canadian Immunization Guide for details.

Management of tetanus:
Supportive care to secure airway, manage spasms, and control autonomic dysfunction

Administered human tetanus Ig

Provide tetanus vaccination (natural infection does not produce immunity)

Antibiotics and debridement of wound (metronidazole or penicillin G)