Immunoreactive complications can occur like Guillain-Barre Syndrome, reactive arthritis, myocarditis, pericarditis, and erythema nodosum during convalescence
Treatment can shorten the duration of illness (usually only by 1 day) and excretion of susceptible organisms and prevent relapse when given early in gastrointestinal tract infection
Recommend treatment for patients with prolonged or severe disease and immunocompromised patients