Consider the following factors prior to ordering C. difficile PCR
If you think the patient has CDI, it’s best to find it within the first three days of hospitalization
BPA: Best Practice Advisory
Soft stop (BPA suggests testing not indicated): Consider stopping diarrhea-causing medication, modifying tube feeds, & reassess number of stools
BPA: Best Practice Advisory
Hard stop on C. difficile PCR if:
Order cancelled if no stool sample sent within 24hrs
Patients with severe CDI with ileus and/or toxic megacolon may not experience diarrhea; consider ID consult for such cases